It affects the bacterial enzyme DNA gyrase, which provides supercoiling forms a complex with its tetramer (subunit of gyrase A2B2) and disrupts the transcription and DNA replication, equipoise leading to bacterial cell death. Beta-lactamases produced by pathogens, have no effect on the activity of lomefloxacin. Highly active against gram-negative aerobic organisms: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter diversus, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Salmonella spp, Shigella spp, Moraxella catarrhalis, Morganella morganii, Haemophilus influenzae and Haemophilus parainfluenzae, Legionella pneumophila…Moderate sensitive to the drug Staphylococcus aureus, Staphylococcus epidermidis, Serratia liquifaciens and Serratia marcescens, Pseudomonas aeruginosa, Mycobacterium tuberculosis , Chlamydia trachomatis, Hafnia alvei, Citrobacter freundii, Aeromonas hydrophila, Proteus mirabilis and Proteus stuartii, Providencia rettgeri and Providencia alcalifaciens, Klebsiella oxytoca, Klebsiella ozaenae , Enterobacter aerogenes, Enterobacter agglomerans. drug resistance Streptococcus spp., Pseudomonas cepacia, Ureaplasma urealyticum, Treponema pallidum, Mycoplasma hominis and anaerobic bacteria.
Indications for use
of the anterior eye bacterial infections (conjunctivitis, blepharitis, bluff-rokonyunktivit, including chlamydial infection). Contraindications:
Hypersensitivity to the drug, pregnancy, lactation, childhood and adolescence (18).
Use in pregnancy and breast-feeding
is not recommended during pregnancy. In the appointment during lactation should stop breastfeeding.
Dosage and administration:
Adults: 1 drop 2-3 times a day equipoise in the lower conjunctival sac for 7-9 days. Early treatment requires more frequent administration of 5 drops within 20 min (1 drop at intervals of 5 minutes) or 1 hour dropwise for 6-10 hours.
For the treatment of chlamydial conjunctivitis 1 drop formulation was instilled into the conjunctival sac of the affected eye 2 -4 times daily for 1-2 months.
Burning sensation; long-term use -. the development of secondary fungal infections
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned equipoise in the instructions, inform your doctor. Overdose We have no data.